CNOT4 (E95) polyclonal antibody
Product Specifications
Background
CNOT4 (CCR4 NOT transcription complex subunit 4) has intrinsic E3 ubiquitin ligase activity. Binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective. The CCR4-NOT complex functions as a global regulator of RNA polymerase II transcription.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CCR4 NOT transcription complex subunit 4; CLONE243; CNOT 4; NOT 4; NOT4; NOT4 (negative regulator of transcription 4 yeast) homolog; NOT4H
Swiss Prot
O95628
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 61-110 of Human CNOT4.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CNOT4 (E95) polyclonal antibody detects endogenous levels of CNOT4 protein.
Applications Notes
Western blot (WB) analysis of CNOT4 (E95) polyclonal antibody in extracts from PC12 cells.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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