EphB1/2/3/4 (Y594) polyclonal antibody
Product Specifications
Background
Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
EphB1; EphB2; EphB3; EphB4
Swiss Prot
P54762/P29323/P54753/P54760
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.
Conjugation
Unconjugated
Related Pathways
Tumor Angiogenesis, Tumor Angiogenesis
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 118 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
EphB1/2/3/4 (Y594) polyclonal antibody detects endogenous levels of EphB1/2/3/4 protein.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Potassium Bicyclo[2.2.1]heptan-2-yltrifluoroborate](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
HMC20112-01 0.5 g
Potassium Bicyclo[2.2.1]heptan-2-yltrifluoroborate
Sign In for Pricing
View Details