Haptoglobin (V328) polyclonal antibody
Product Specifications
Background
Haptoglobin (Hp) is a blood plasma protein that functions to bind free Hemoglobin that has been released from erythrocytes, thereby inhibiting its oxidative activity. During this process, Haptoglobin sequesters the iron within Hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. This function suggests that Haptoglobin concentrations may increase in response to inflammation. The resulting Haptoglobin-Hemoglobin complex is then removed by the reticulo-endothelial system. Due to cleavage of a common precursor protein during protein synthesis, Haptoglobin consists of two α and two β chains, connected by disulfide bridges.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Haptoglobin; Zonulin; Haptoglobin alpha chain; Haptoglobin beta chain; HP
Swiss Prot
P00738
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 301-350 of Human Haptoglobin.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Haptoglobin (V328) polyclonal antibody detects endogenous levels of Haptoglobin protein.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNCB1718-500 1x 500 µL
Bcl-6 (Follicular Lymphoma Marker) (BCL6/1718), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 