What is the catalog number for JNK1/2/3 (T178) polyclonal antibody?

The catalog number for JNK1/2/3 (T178) polyclonal antibody is BS3630.

What sizes are available for JNK1/2/3 (T178) polyclonal antibody?

JNK1/2/3 (T178) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does JNK1/2/3 (T178) polyclonal antibody come in?

JNK1/2/3 (T178) polyclonal antibody is available in 2 different pack sizes.

Is JNK1/2/3 (T178) polyclonal antibody in stock?

JNK1/2/3 (T178) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

JNK1/2/3 (T178) polyclonal antibody

Product Specifications

Background

The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38. JNK3 (MK10, MAPK10, PRKM10) is activated by pro-inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c-Jun and ATF2. This is important for AP-1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress-induced) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

JNK 46; JNK 55; JNK; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3A; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 8; MAPK 9; MAPK10; MAPK8; MAPK9; MGC50974; Mitogen activated protein kinase 10; Mitogen activated protein kinase 8; Mitogen activated protein kinase 9

Swiss Prot

P45983/P45984/P53779

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.

Conjugation

Unconjugated

Related Pathways

Immune Cell Signaling, SAPK JNK Signaling Cascades, Inhibition of Apoptosis, G Protein-coupled Receptors Signaling to MAPK Erk, MAPK Erk in Growth and Differentiation Pathway, MAPK Erk in Growth and Differentiation Pathway, Mitochondrial Control of Apoptosis, ErbB HER Signaling, ErbB HER Signaling

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 46,54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

JNK1/2/3 (T178) polyclonal antibody detects endogenous levels of JNK1/2/3 protein.

Applications Notes

Western blot (WB) analysis of JNK1/2/3 (T178) pAb at 1:500 dilution Lane1:K562 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:The Brain tissue lysate of Rat (40ug) Lane4:The Brain tissue lysate of Mouse (40ug)