Sarcoglycan-β (V136) polyclonal antibody
Product Specifications
Background
Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Beta-sarcoglycan; β-sarcoglycan; Beta-SG; SG-β; SGβ; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b; SGCB
Swiss Prot
Q16585
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 102-158 of Human Sarcoglycan-β.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Sarcoglycan-β (V136) polyclonal antibody detects endogenous levels of Sarcoglycan-β protein.
Host or Source
Rabbit
Available Sizes
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