Neuropilin-1 (D525) polyclonal antibody

Product Specifications

Background

Neuropilin 1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both Vascular Endothelial Growth Factor and Semaphorin family members. Neuropilin 1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; CD_antigen=CD304; NRP1; NRP; VEGF165R

Swiss Prot

O14786

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 501-550 of Human Neuropilin-1.

Conjugation

Unconjugated

Related Pathways

Tumor Angiogenesis

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 130 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Neuropilin-1 (D525) polyclonal antibody detects endogenous levels of Neuropilin-1 protein.

Applications Notes

Western blot (WB) analysis of Neuropilin-1 (D525) pAb at 1:1000 dilution Lane1:L02 whole cell lysate (20ug) Lane2:A549 whole cell lysate (20ug) Lane3:PC3 whole cell lysate (20ug) Lane4:The Heart tissue lysate of Rat (40ug) Lane5:The Brain tissue lysate of Mouse (40ug)