CA II (N229) polyclonal antibody

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes including respiration, calcification, acid-base balance and bone resorption, as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA2 gene, which maps to chromosome 8q21, encodes CA II, a cytoplasmic protein that has the highest turnover rate and widest tissue distribution of any known human CA isozyme.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of CA II (N229) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate (40ug) Lane2:The Kidney tissue lysate of Mouse (40ug) Lane3:The Brain tissue lysate of Rat (20ug) Lane4:HEK293T whole cell lysate (10ug)