What is the catalog number for PKA IIβ reg (T109) polyclonal antibody?

The catalog number for PKA IIβ reg (T109) polyclonal antibody is BS3253.

What sizes are available for PKA IIβ reg (T109) polyclonal antibody?

PKA IIβ reg (T109) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does PKA IIβ reg (T109) polyclonal antibody come in?

PKA IIβ reg (T109) polyclonal antibody is available in 2 different pack sizes.

Is PKA IIβ reg (T109) polyclonal antibody in stock?

PKA IIβ reg (T109) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PKA IIβ reg (T109) polyclonal antibody

Product Specifications

Background

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA) . Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93% amino acid sequence similarity), whereas Cγ displays 83% and 79% similarity to Cα and Cβ, respectively.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory subunit

Swiss Prot

P31323

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 80-130 of Human PKA IIβ reg.

Conjugation

Unconjugated

Related Pathways

Inhibition of Apoptosis, Mitochondrial Control of Apoptosis

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 46 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PKA IIβ reg (T109) polyclonal antibody detects endogenous levels of PKA IIβ reg protein.

Applications Notes

Western blot (WB) analysis of PKA IIβ reg (T109) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate Lane4:A549 whole cell lysate Lane5:sp2/0 whole cell lysate