GNPAT (F365) polyclonal antibody
Product Specifications
Background
GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Dihydroxyacetone phosphate acyltransferase; DAP-AT; DHAP-AT; Acyl-CoA:dihydroxyacetonephosphateacyltransferase; Glycerone-phosphate O-acyltransferase; GNPAT; DAPAT; DHAPAT
Swiss Prot
O15228
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 341-390 of Human GNPAT.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 77 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GNPAT (F365) polyclonal antibody detects endogenous levels of GNPAT protein.
Applications Notes
Western blot (WB) analysis of GNPAT (F365) pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate (40ug) Lane2:H9C2 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug) Lane4:Hela whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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