ABCA8 (F1195) polyclonal antibody
Product Specifications
Background
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1,581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ATP-binding cassette sub-family A member 8; KIAA0822
Swiss Prot
O94911
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 1171-1220 of Human ABCA8.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 179 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ABCA8 (F1195) polyclonal antibody detects endogenous levels of ABCA8 protein.
Applications Notes
Western blot (WB) analysis of ABCA8 (F1195) pAb at 1:500 dilution Lane1:H9C2 whole cell lysate (40ug) Lane2:AML-12 whole cell lysate (40ug) Lane3:SK-OVCAR3 whole cell lysate (40ug) Lane4:HepG2 whole cell lysate (40ug) Lane5:L02 whole cell lysate (10ug)
Host or Source
Rabbit
Available Sizes
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