Fgl2 (V38) polyclonal antibody
Product Specifications
Background
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively xpressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Fibroleukin; Fibrinogen-like protein 2; pT49; FGL2
Swiss Prot
Q14314
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 6-60 of Human Fgl2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Fgl2 (V38) polyclonal antibody detects endogenous levels of Fgl2 protein.
Applications Notes
Western blot (WB) analysis of Fgl2 (V38) pAb at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:SP2/0 whole cell lysate (40ug) Lane3:C6 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:Hela whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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