AVP Receptor V3 (D314) polyclonal antibody
Product Specifications
Background
Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality. AVP mediates its effects through a family of G protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b) . The AVP receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores. AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor; AVPR1B; AVPR3; VPR3
Swiss Prot
P47901
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 300-350 of Human AVP Receptor V3.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:1000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 47 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
AVP Receptor V3 (D314) polyclonal antibody detects endogenous levels of AVP Receptor V3 protein.
Applications Notes
Western blot (WB) analysis of AVP Receptor V3 (D314) polyclonal antibody at 1:500 dilution Lane1:HepG2 cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat lung tissue lysate
Host or Source
Rabbit
Available Sizes
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