TCR β (K115) polyclonal antibody
Product Specifications
Background
TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. The vast majority of circulating T cells (95%) express the alpha/beta heterodimer while roughly 2-5% express the gamma/delta heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
T-cell receptor beta-1 chain C region; TRBC1
Swiss Prot
P01850
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 81-130 of Human TCR β.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TCR β (K115) polyclonal antibody detects endogenous levels of TCR β protein.
Applications Notes
Western blot (WB) analysis of TCR β (K115) pAb at 1:500 dilution Lane1:H1792 whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:H9C2 whole cell lysate (40ug) Lane4:3T3-L1 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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