What is the catalog number for GRP1 (K400) polyclonal antibody?

The catalog number for GRP1 (K400) polyclonal antibody is BS2942.

What sizes are available for GRP1 (K400) polyclonal antibody?

GRP1 (K400) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does GRP1 (K400) polyclonal antibody come in?

GRP1 (K400) polyclonal antibody is available in 2 different pack sizes.

Is GRP1 (K400) polyclonal antibody in stock?

GRP1 (K400) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

GRP1 (K400) polyclonal antibody

Product Specifications

Background

GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain as well as a Sec7 domain. The PH domain has high binding affinity for phosphatidylinositol 3,4,5-trisphosphate Ptdlns (3,4,5) P3), while the Sec7 homology domain is responsible for catalyzing guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins. GRP1 co-localizes with ARF6 and catalyzes GTP/GDP exchange on ARF6. It is known to interact with Ptdlns (3,4,5) P3 localized to the plasma membrane in vitro and may also be a Ptdlns (3,4,5) P3 receptor. Additionally, GRP1 may regulate protein sorting and membrane trafficking through interaction with the guanosine triphosphate ARF, and may control cell adhesion through interaction with integrins.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cytohesin-3; ARF nucleotide-binding site opener 3; Protein ARNO3; General receptor of phosphoinositides 1; Grp1; PH; SEC7 and coiled-coil domain-containing protein 3; ARNO3; GRP1; PSCD3; CYTH3

Swiss Prot

O43739

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 371-420 of Human GRP1.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 48 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

GRP1 (K400) polyclonal antibody detects endogenous levels of GRP1 protein.

Applications Notes

Western blot (WB) analysis of GRP1 (K400) pAb at 1:2000 dilution Lane1:3T3-L1 whole cell lysate (40ug) Lane2:H9C2 whole cell lysate (40ug) Lane3:A2780 whole cell lysate (40ug) Lane4:H1792 whole cell lysate (40ug) Lane5:A375 whole cell lysate (20ug)