VAMP-1/2/3 (D70) polyclonal antibody
Product Specifications
Background
VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including a- and g-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and Syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP1; SYB1; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP2; SYB2; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptobrevin-3; VAMP3; SYB3
Swiss Prot
P23763/P63027/Q15836
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 40-90 of Human VAMP1.
Conjugation
Unconjugated
Related Pathways
Vesicle Trafficking presynaptic signaling, AMPK Signaling Pathway
Applications
IHC
Dilution
IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 13 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
VAMP-1/2/3 (D70) polyclonal antibody detects endogenous levels of VAMP-1/VAMP-2/VAMP-3 protein
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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