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PGE synthase (I79) polyclonal antibody

Product Specifications

Background

Prostaglandin E synthase (PGE synthase), also known as PIG12 and MGST1-L1, is a member of protein super family MAPEG, which consists of membrane associated proteins involved in eicosanoid and glutathione metabolism. The expression of this membrane-associated protein can be induced by the pro-inflammatory cytokine, IL-1β. PGE synthase is expressed in seminal vesicles, deferent ducts, kidney, heart and spleen. The enzyme activity of PGE synthase in most organs is glutathione-dependent. PGE synthase may play a significant role in the progression of Alzheimer’s disease.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Short name=MGST1-L1; Microsomal prostaglandin E synthase 1; Short name=MPGES-1; p53-induced gene 12 protein; PTGES; MGST1L1; MPGES1; PGES; PIG12

Swiss Prot

O14684

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 51-100 of Human PGE synthase.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~17 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PGE synthase (I79) polyclonal antibody detects endogenous levels of PGE synthase protein.

Applications Notes

Western blot (WB) analysis of PGE synthase (I79) polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:H9C2 whole cell lysate (40ug) Lane4:SP2/0 whole cell lysate (40ug)

Host or Source

Rabbit

Available Sizes

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