PGE synthase (I79) polyclonal antibody
Product Specifications
Background
Prostaglandin E synthase (PGE synthase), also known as PIG12 and MGST1-L1, is a member of protein super family MAPEG, which consists of membrane associated proteins involved in eicosanoid and glutathione metabolism. The expression of this membrane-associated protein can be induced by the pro-inflammatory cytokine, IL-1β. PGE synthase is expressed in seminal vesicles, deferent ducts, kidney, heart and spleen. The enzyme activity of PGE synthase in most organs is glutathione-dependent. PGE synthase may play a significant role in the progression of Alzheimer’s disease.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Short name=MGST1-L1; Microsomal prostaglandin E synthase 1; Short name=MPGES-1; p53-induced gene 12 protein; PTGES; MGST1L1; MPGES1; PGES; PIG12
Swiss Prot
O14684
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 51-100 of Human PGE synthase.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~17 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PGE synthase (I79) polyclonal antibody detects endogenous levels of PGE synthase protein.
Applications Notes
Western blot (WB) analysis of PGE synthase (I79) polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:H9C2 whole cell lysate (40ug) Lane4:SP2/0 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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