EMR3 (Y652) polyclonal antibody
Product Specifications
Background
EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF) -like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms.EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; UNQ683/PRO1562; EMR3
Swiss Prot
Q9BY15
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 620-671 of Human EMR3.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
EMR3 (Y652) polyclonal antibody detects endogenous levels of EMR3 protein.
Applications Notes
Western blot (WB) analysis of EMR3 (Y652) pAb at 1:500 dilution Lane1:H9C2 whole cell lysate (40ug) Lane2:CT26 whole cell lysate (40ug) Lane3:HepG2 whole cell lysate (40ug) Lane4:MCF-7 whole cell lysate (40ug) Lane5:K562 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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