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Gas6 (G309) polyclonal antibody

Product Specifications

Background

Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; AXLLG; GAS6

Swiss Prot

Q14393

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Gas6 (G309) polyclonal antibody detects endogenous levels of Gas6 protein.

Applications Notes

Western blot (WB) analysis of Gas6 (G309) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Mouse heart tissue lysate Lane3:PC12 whole cell lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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