Galectin-7 (Q67) polyclonal antibody

Product Specifications

Background

Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galectin-7, expressed mainly in stratified squamous epithelium, is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. The galectin-7 gene maps to chromosome 19.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Galectin7; Gal-7; HKL-14; Galectin 7; Gal7; HKL14; PI7; p53-induced gene 1 protein; LGALS7; PIG1; LGALS7B

Swiss Prot

P47929

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 50-100 of Human Galectin-7.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .