NY-CO-1 (K914) polyclonal antibody
Product Specifications
Background
Protein names: Nuclear export mediator factor NEMF; Serologically defined colon cancer antigen 1; Gene names: NEMF; SDCCAG1. Function: Plays a role in nuclear export. Subunit structure: Interacts (via its N-terminus) with XPO1. Subcellular location: Nucleus.Tissue specificity: Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis. Domain: The N-terminal domain contains a nuclear export signal. The C-terminal domain may interact with cargo proteins. Miscellaneous: Active in normal lung tissue, but is inactive in several lung cancer cell lines.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1; NEMF; SDCCAG1
Swiss Prot
O60524
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 881-930 of Human NY-CO-1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NY-CO-1 (K914) polyclonal antibody detects endogenous levels of NY-CO-1 protein.
Applications Notes
Western blot (WB) analysis of NY-CO-1 (K914) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit
Available Sizes
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