What is the catalog number for Hel-N1 (S27) polyclonal antibody?

The catalog number for Hel-N1 (S27) polyclonal antibody is BS2299.

What sizes are available for Hel-N1 (S27) polyclonal antibody?

Hel-N1 (S27) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Hel-N1 (S27) polyclonal antibody come in?

Hel-N1 (S27) polyclonal antibody is available in 2 different pack sizes.

Is Hel-N1 (S27) polyclonal antibody in stock?

Hel-N1 (S27) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Hel-N1 (S27) polyclonal antibody

Product Specifications

Background

The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM), and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

ELAV like 4; ELAV like neuronal protein 1; ELAV like protein 2; ELAV like protein 4; ELAVL 2; ELAVL 4; HELN1; Hu antigen B; Hu antigen D; HUB; HUD; Hel-N1; ELAVL2; HEL-N1; HELN1; HUB

Swiss Prot

Q12926

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to the N-terminus of Human Hel-N1.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 38 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Hel-N1 (S27) polyclonal antibody detects endogenous levels of HuB protein.

Applications Notes

Western blot (WB) analysis of Hel-N1 (S27) pAb at 1:500 dilution Lane1:The Brain tissue lysate of Mouse (40ug) Lane2:C6 whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug) Lane4:PC3 whole cell lysate (40ug)