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FoxK1 (G698) polyclonal antibody

Product Specifications

Background

FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP) . Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FHX; Fork head; Forkhead box protein K1; FOXJ2 forkhead factor; FOXK1; FOXK1; MNF; Myocyte nuclear factor

Swiss Prot

P85037

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 668-720 of Human FoxK1.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 75, 97 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

FoxK1 (G698) polyclonal antibody detects endogenous levels of FoxK1 protein.

Applications Notes

Western blot (WB) analysis of FoxK1 (G698) pAb at 1:500 dilution Lane1:K562 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug) Lane4:MCF-7 whole cell lysate (40ug) Lane5:CT26 whole cell lysate (40ug) Lane6:C6 whole cell lysate (40ug)

Host or Source

Rabbit

Available Sizes

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