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LTβR (R44) polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta) . The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Tumor necrosis factor receptor superfamily member 3; Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; TNF-RIII; TNFR-III; D12S370; TNFCR; TNFR3; TNFRSF3; LTBR

Swiss Prot

P36941

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 20-60 of Human LTβR.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB: 1:500~1:1000 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

LTβR (R44) polyclonal antibody detects endogenous levels of LTβR protein.

Applications Notes

Western blot (WB) analysis of LTβR (R44) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (36ug) Lane2:RAW264.7 whole cell lysate (36ug) Lane3:PC12 whole cell lysate (36ug) Lane4:NIH-3T3 whole cell lysate (36ug) Lane5:HEK293T whole cell lysate (36ug)

Host or Source

Rabbit

Available Sizes

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