TAF II p135/p105 (E977) polyclonal antibody

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFκB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA) . Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

Transcription initiation factor TFIID subunit 4; RNA polymerase II TBP-associated factor subunit C; TBP-associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; TAF (II) 130; TAFII-130; TAFII130; Transcription initiation factor TFIID 135 kDa subunit; TAF (II) 135; TAFII-135; TAFII135; TAF4; TAF2C; TAF2C1; TAF4A; TAFII130; TAFII135; Transcription initiation factor TFIID subunit 4B; Transcription initiation factor TFIID 105 kDa subunit; TAF (II) 105; TAFII-105; TAFII105; TAF4B; TAF2C2; TAFII105

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of TAF II p135/p105 (E977) polyclonal antibody at 1:500 dilution Lane1:A2780 whole cell lysate (40ug) Lane2:The Ovary tissue lysate of Rat (40ug) Lane3:SK-OVCAR3 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug)