ADCY 5/6 (F1052) polyclonal antibody

A cyclase V, also known as ADCY5, is a 1,261 amino acid Adenylyl cyclase that localizes to cellular membranes and contains two guanylate cyclase domains. Similar to other A cyclase proteins, A cyclase V uses magnesium as a cofactor to catalyze the conversion of ATP to cAMP. A cyclase VI, also known as ADCY6 (adenylate cyclase type 6), is a 1,168 amino acid A cyclase that localizes to the membrane and contains two guanylate cyclase domains. Using magnesium as a cofactor, A cyclase VI functions as a calcium-inhibitable A cyclase that catalyzes the conversion of ATP to 3',5'-cyclic AMP and diphosphate and plays a role in a variety of events throughout the body. Multiple isoforms of A cyclase VI exist due to alternative splicing events.

A cyclase V; A cyclase VI; Adenylate cyclase type 5; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; ADCY5; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca (2+) -inhibitable adenylyl cyclase; ADCY6; KIAA0422

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of ADCY 5/6 (F1052) polyclonal antibody at 1:500 dilution Lane1:Panc1 whole cell lysate (40ug) Lane2:PC3 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:Hela whole cell lysate (40ug) Lane5:MCF-7 whole cell lysate (40ug) Lane6:The Pancreas tissue lysate of Mouse (40ug) Lane7:The Pancreas tissue lysate of Rat (40ug)