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CYP1A1/2 (R98) polyclonal antibody

Product Specifications

Background

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous levels of and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; CYP1A1; Cytochrome P450 1A2; CYPIA2; Cytochrome P (3) 450; Cytochrome P450 4; Cytochrome P450-P3; CYP1A2

Swiss Prot

P04798/P05177

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 71-120 of Human CYP1A1.

Conjugation

Unconjugated

Applications

IHC IF

Dilution

IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 58 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CYP1A1/2 (R98) polyclonal antibody detects endogenous levels of CYP1A1 and CYP1A2 protein.

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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