Sideroflexin-4 (G12) polyclonal antibody

Product Specifications

Background

Sideroflexin-4, potential iron transporter. SFXN4 is an uncharacterized mitochondrial protein that localizes to the mitochondrial inner membrane. Modulation of SFXN4 alters mitochondrial respiration by affecting iron-sulfur cluster biogenesis. SFXN4 may be a potential druggable target in ovarian cancer.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Sideroflexin-4; Breast cancer resistance marker 1; SFXN4; BCRM1

Swiss Prot

Q6P4A7

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 5-75 of Human Sideroflexin-4.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 38 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Sideroflexin-4 (G12) polyclonal antibody detects endogenous levels of Sideroflexin-4 protein.

Applications Notes

Western blot (WB) analysis of Sideroflexin-4 (G12) polyclonal antibody at 1:1000 dilution Lane1:HCT116 whole cell lysate (40ug) Lane2:HepG2 whole cell lysate (40ug) Lane3:L02 whole cell lysate (10ug) Lane4:H1792 whole cell lysate (10ug)