SCAND1 (E88) polyclonal antibody

SCAND1 (SCAN domain containing 1), also known as RAZ1 or SDP1, is a nuclear protein that may play a role in the mechanism of transcription regulation. It is widely expressed with highest levels of expression found in kidney, thyroid, liver, prostate and testis. SCAND1 contains one SCAN box domain and, unlike the majority of other SCAN domain containing proteins, it does not contain a zinc finger motif. The SCAN box domain is a conserved leucine rich motif, approximately 60 amino acids in length, that participates in proteinprotein interactions. SCAND1 interacts with ZNF38, ZNF191 and MZF-1. It also interacts with ZNF202 and PPARγ, suggesting that it plays a role in the transcriptional regulation of genes that are involved in energy homeostasis and lipid metabolism.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .