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AF-10 (E237) polyclonal antibody

Product Specifications

Background

AF10 is a putative transcription factor containing a leucine zipper motif. A t (10;11) (p12; q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Protein AF-10; ALL1-fused gene from chromosome 10 protein; MLLT10; AF10

Swiss Prot

P55197

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 200-250 of Human AF-10.

Conjugation

Unconjugated

Applications

IHC IF

Dilution

IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 109 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

AF-10 (E237) polyclonal antibody detects endogenous levels of AF-10 protein.

Host or Source

Rabbit

Available Sizes

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