MZF-1 (D10) polyclonal antibody
Product Specifications
Background
Zinc finger genes encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Krüppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43, while the gene encoding for ZBP-89 is localized on chromosome 3q21.2. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. It regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. MZF-1 is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Myeloid zinc finger 1; MZF-1; Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42; MZF1; MZF; ZNF42; ZSCAN6
Swiss Prot
P28698
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 5-55 of Human MZF-1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 82 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MZF-1 (D10) pAb detects endogenous levels of MZF-1 protein.
Applications Notes
Western blot (WB) analysis of MZF-1 (D10) pAb at 1:500 dilution Lane1:MG63 whole cell lysate (30ug) Lane2:Panc1 whole cell lysate (40ug) Lane3:C6 whole cell lysate (40ug) Lane4:3T3-L1 whole cell lysate (40ug) Lane5:K562 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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