ARP-1 (T7) polyclonal antibody
Product Specifications
Background
COUP (chicken ovalbumin upstream promoter) transcription factors have been cloned in several species and identified as orphan members of the steroid/thyroid hormone receptor superfamily. COUP-TFI (also designated COUP or EAR-3) and ARP-1 (also designated COUP-TFII) exhibit highly regulated and overlapping expression in most tissues. COUP-TFs are highly expressed in the developing and central nervous system, suggesting that these factors may be important in neural development and differentiation. COUP-TFs can compete for binding to response elements which are common to other members of this family, including RAR, RXR, PPAR, HNF-4, VDR and TR. They have been shown to act as negative regulators as well as initiators of transcription.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
COUP transcription factor 2; COUP-TF2; Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2; NR2F2; ARP1; TFCOUP2; COUP TF2; COUPTF2
Swiss Prot
P24468
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the N-terminal of Human ARP-1.
Conjugation
Unconjugated
Related Pathways
Nuclear Receptor Signaling
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ARP-1 (T7) polyclonal antibody detects endogenous levels of ARP-1 protein.
Applications Notes
Western blot (WB) analysis of ARP-1 (T7) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (20ug) Lane3:H9C2 whole cell lysate (20ug) Lane4:MEF whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
Curated Selection
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