What is the catalog number for TNF-R2 (P412) polyclonal antibody?

The catalog number for TNF-R2 (P412) polyclonal antibody is BS1949.

What sizes are available for TNF-R2 (P412) polyclonal antibody?

TNF-R2 (P412) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does TNF-R2 (P412) polyclonal antibody come in?

TNF-R2 (P412) polyclonal antibody is available in 2 different pack sizes.

Is TNF-R2 (P412) polyclonal antibody in stock?

TNF-R2 (P412) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

TNF-R2 (P412) polyclonal antibody

Product Specifications

Background

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD120b; INN=Etanercept; Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2; TBP-2; TBPII; TNFRSF1B; TNFBR; TNFR2

Swiss Prot

P20333

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 390-440 of Human TNF-R2.

Conjugation

Unconjugated

Related Pathways

Tumor Angiogenesis, Death Receptor Signaling

Applications

IHC

Dilution

IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .