What is the catalog number for HnRNP L (G58) polyclonal antibody?

The catalog number for HnRNP L (G58) polyclonal antibody is BS1931.

What sizes are available for HnRNP L (G58) polyclonal antibody?

HnRNP L (G58) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does HnRNP L (G58) polyclonal antibody come in?

HnRNP L (G58) polyclonal antibody is available in 2 different pack sizes.

Is HnRNP L (G58) polyclonal antibody in stock?

HnRNP L (G58) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

HnRNP L (G58) polyclonal antibody

Product Specifications

Background

Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing and mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II) . There are approximately 20 known hnRNP proteins, which range in size from 34 kDa to 120 kDa, and their complexes are the majorconstituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB) and its homolog hnRNP L bind to the 3' end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells and the translation of several viruses, including hepatitis C virus (HCV) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Heterogeneous nuclear ribonucleoprotein L; hnRNP L; HNRNPL; HNRPL; P/OKcl.14

Swiss Prot

P14866

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 30-80 of Human hnRNP L.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 60 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

HnRNP L (G58) polyclonal antibody detects endogenous levels of hnRNP L protein.

Applications Notes

Western blot (WB) analysis of hnRNP L (G58) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate (10ug) Lane2:A549 whole cell lysate (10ug) Lane3:K562 whole cell lysate (10ug) Lane4:The Uterus tissue lysate of Rat (20ug) Lane5:The Brain tissue lysate of Mouse (40ug)