EAR2 (S40) polyclonal antibody
Product Specifications
Background
EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2) protein binds a cis enhancer element (TGACCT motif) upstream of the rennin gene and represses renin gene transcription. EAR2 also contributes to gonadotropin-dependent derepression of LHR promoter activity in granulose cells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to the nucleus of As4.1 cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Probable glutamyl-tRNA synthetase; mitochondrial; Glutamate--tRNA ligase; GluRS; EARS2; KIAA1970
Swiss Prot
P10588
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 21-70 of Human EAR2.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
EAR2 (S40) polyclonal antibody detects endogenous levels of EAR2 protein.
Applications Notes
Western blot (WB) analysis of EAR2 (S40) pAb at 1:500 dilution Lane1:PC12 whole cell lysate (40ug) Lane2:AML-12 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:HepG2 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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