Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Snail1 (A242) polyclonal antibody

Product Specifications

Background

The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. The Snail-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna; SNAI1; SNAH; SNAI 1; Snail 1; Snail-1

Swiss Prot

O95863

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human Snail1 around the phosphorylation site of Serine 246.

Conjugation

Unconjugated

Related Pathways

Contribution of Soluble Factors to EMT, ESC Pluripotency and Differentiation Signaling Pathway

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 29 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Snail1 (A242) polyclonal antibody detects endogenous levels of Snail1 protein.

Applications Notes

Western blot (WB) analysis of Snail1 (A242) polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:NIH-3T3 cell lysate Lane3:Rat heart tissue lysate

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Phrixotoxin 3
M30600-01 100 mg

Phrixotoxin 3

Ask
View Details
Phrixotoxin 3
M30600-02 200 mg

Phrixotoxin 3

Ask
View Details
Phrixotoxin 3
M30600-03 500 mg

Phrixotoxin 3

Ask
View Details
Phrixotoxin 3
M30600-04 Inquire

Phrixotoxin 3

Ask
View Details
Phrixotoxin 3
M30600-05 10 mg

Phrixotoxin 3

Ask
View Details
P53 (TRP/817), CF405S conjugate, 0.1mg/mL
BNC040817-100 1x 100 µL

P53 (TRP/817), CF405S conjugate, 0.1mg/mL

Ask
View Details