IL-13Rα1 (K401) polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD213a1; IL13RA1; IL13R; IL13RA
Swiss Prot
P78552
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 380-420 of Human IL-13Rα1.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 49 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IL-13Rα1 (K401) polyclonal antibody detects endogenous levels of IL-13Rα1 protein.
Applications Notes
Western blot (WB) analysis of IL-13Rα1 (K401) polyclonal antibody at 1:500 dilution Lane1:The Liver tissue lysate of Rat (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:CT-26 whole cell lysate (40ug) Lane4:L02 whole cell lysate (40ug) Lane5:Hela whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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