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COL1A2 (S3) polyclonal antibody

Product Specifications

Background

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Alpha-2 type I collagen; COL1A2

Swiss Prot

P08123

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to the N-terminus of Human COL1A2.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 125 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

COL1A2 (S3) polyclonal antibody detects endogenous levels of Collagen alpha-2 (I) chain protein.

Applications Notes

Western blot (WB) analysis of COL1A2 (S3) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Mouse liver tissue lysate Lane3:Mouse lung tissue lysate Lane4:Rat liver tissue lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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