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PYK2 (I574) polyclonal antibody

Product Specifications

Background

Pyk2 is a protein tyrosine kinase related to Focal Adhesion Kinase (p125 FAK) . Pyk2 is highly expressed in the central nervous system. It is phosphorylated on tyrosine residues in response to various stimuli that elevate intracellular calcium concentration, as well as by protein kinase C activation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cell adhesion kinase beta; CAK beta; Calcium-dependent tyrosine kinase; CADTK; Related adhesion focal tyrosine kinase; RAFTK; PYK2; FAK2; PYK2; RAFTK

Swiss Prot

Q14289

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 360-418 of Human TFDP1.

Conjugation

Unconjugated

Related Pathways

G Protein-coupled Receptors Signaling to MAPK Erk, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 115 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PYK2 (I574) polyclonal antibody detects endogenous levels of PYK2 protein.

Applications Notes

Western blot (WB) analysis of PYK2 (I574) pAb at 1:500 dilution Lane1:K562 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:Hela whole cell lysate (40ug) Lane4:The Brain tissue lysate of Mouse (40ug) Lane5:The Brain tissue lysate of Rat (40ug)

Host or Source

Rabbit

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