MEK-6 (S201) polyclonal antibody

Product Specifications

Background

Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs) . MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3; MAP2K6; MEK6; MKK6; PRKMK6; SKK3

Swiss Prot

P52564

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 270-320 of Human MEK-6.

Conjugation

Unconjugated

Related Pathways

Signaling Pathways Activating p38 MAP Kinase

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 37 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MEK-6 (S201) polyclonal antibody detects endogenous levels of MEK-6 protein.

Applications Notes

Western blot (WB) analysis of MEK-6 (S201) polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate (40ug) Lane2:Panc1 whole cell lysate (40ug) Lane3:CT26 whole cell lysate (40ug) Lane4:The Heart tissue lysate of Rat (40ug) Lane5:The Muscle tissue lysate of Mouse (40ug)