G3BP-1 (D226) polyclonal antibody
Product Specifications
Background
G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1
Swiss Prot
Q13283
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 196-246 of Human G3BP-1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
G3BP-1 (D226) polyclonal antibody detects endogenous levels of G3BP-1 protein.
Applications Notes
Western blot (WB) analysis of G3BP-1 (D226) polyclonal antibody at 1:500 dilution Lane1:A549 cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat heart tissue lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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