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E2F4/E2F5 (L50/83) polyclonal antibody

Product Specifications

Background

E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an “active” E2F transcriptional regulatory complex.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Transcription factor E2F4; E2F-4; E2F4; Transcription factor E2F5; E2F-5; E2F5

Swiss Prot

Q16254 / Q15329

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 18-72 of Human E2F4.

Conjugation

Unconjugated

Related Pathways

Cell Cycle Control G1 S Checkpoint

Applications

IHC

Dilution

IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 44 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

E2F4/E2F5 (L50/83) polyclonal antibody detects endogenous levels of E2F4/E2F5 protein.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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