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MUC20 polyclonal antibody

Product Specifications

Background

Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most organisms of Kingdom Animalia. Mucins' key characteristic is their ability to form gels; therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. They often take an inhibitory role. Some mucins are associated with controlling mineralization, including nacre formation in mollusks, calcification in echinoderms and bone formation in vertebrates. They bind to pathogens as part of the immune system. Overexpression of the mucin proteins, especially MUC1, is associated with many types of cancer.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Mucin-20; MUC20

Swiss Prot

Q8N307

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human MUC20.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Modification

Unmodification

Molecular Weight

~ 100 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MUC20 polyclonal antibody detects endogenous levels of MUC20 protein.

Applications Notes

Western blot (WB) analysis of MUC20 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate (40ug) Lane2:The kidney tissue lysate of Mouse (40ug) Lane3:The kidney tissue lysate of Rat (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:L02 whole cell lysate (40ug)

Host or Source

Rabbit

Available Sizes

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