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MRP8 polyclonal antibody

Product Specifications

Background

The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 α and β, Cal-granulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins) and the parvalbumin family members, including parvalbumin α and parvalbumin β (also designated oncomodulin) . Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 α and β are present in a variety of other tissues and Calbindin is present in intestine and kidney. Parvalbumin α is also found in fast-contracting/ relaxing skeletal muscle fibers and parvalbumin β is found in many tumor tissues as well as in the organ of Corti.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Protein S100-A8; Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; S100 calcium-binding protein A8; Urinary stone protein band A; Protein S100-A8, N-terminally processed; S100A8; CAGA; CFAG; MRP8

Swiss Prot

P05109

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids CMGVAAHKKSHEESHKE of Human MRP8.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB:1:500~1:1000 IHC:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 101% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 23 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MRP8 polyclonal antibody detects endogenous levels of MRP8 protein.

Applications Notes

Western blot (WB) analysis of MRP8 pAb at 1:500 dilution Lane1:PC12 whole cell lysate (40ug) Lane2:SP2/0 whole cell lysate (40ug) Lane3:EC9706 whole cell lysate (40ug) Lane4:A375 whole cell lysate (40ug) Lane5:HCC827 whole cell lysate (40ug)

Host or Source

Rabbit

Available Sizes

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