KIF20A (I524) polyclonal antibody
Product Specifications
Background
The Kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual Kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events, including endocytosis and transcytosis. KIF20A (kinesin family member 20A), also known as Rabkinesin-6, RAB6KIFL (Rab6-interacting kinesin-like protein), GG10_2 or MKLP2 (mitotic kinesin-like protein 2), is a 890 amino acid protein that contains one kinesin-motor domain and belongs to the Kinesin-like protein family. KIF20A locates to the Golgi apparatus and interacts with guanosine triphosphate (GTP) -bound forms of RAB 6. KIF20A may be responsible for the retrograde RAB 6 regulated transport of Golgi membranes and related vesicles along microtubules.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Kinesin-like protein KIF20A; GG10_2; Mitotic kinesin-like protein 2; MKlp2; Rab6-interacting kinesin-like protein; Rabkinesin-6; KIF20A; MKLP2; RAB6KIFL
Swiss Prot
O95235
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 501-550 of Human KIF20A.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
KIF20A (I524) polyclonal antibody detects endogenous levels of KIF20A protein.
Applications Notes
Western blot (WB) analysis of KIF20A (I524) pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate (10ug) Lane2:EC9706 whole cell lysate (10ug)
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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