GOLPH3 polyclonal antibody
Product Specifications
Background
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. GOLPH3L (golgi phosphoprotein 3-like), also known as GPP34R, is a 285 amino acid cytoplasmic protein that localizes to the Golgi apparatus. Belonging to the GOLPH3/VPS74 family, GOLPH3L may have a regulatory role in Golgi trafficking. GOLPH3L is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Golgi phosphoprotein 3; Coat protein GPP34; Mitochondrial DNA absence factor; MIDAS
Swiss Prot
Q9H4A6
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human GOLPH3.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Modification
Unmodification
Molecular Weight
~ 34 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GOLPH3 polyclonal antibody detects endogenous levels of GOLPH3 protein.
Applications Notes
Western blot (WB) analysis of GOLPH3 pAb at 1:2000 dilution Lane1:SGC7901 whole cell lysate (40ug) Lane2:3T3-L1 whole cell lysate (40ug) Lane3:HCT116 whole cell lysate (40ug) Lane4:PC3 whole cell lysate (40ug) Lane5:H9C2 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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