Nrf2 (L593) polyclonal antibody
Product Specifications
Background
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP subfamily of basic /leucine zipper (bZIP) transcription factors.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; NFE2L2; NRF2
Swiss Prot
Q16236
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 560-621 of Human Nrf2.
Conjugation
Unconjugated
Related Pathways
AMPK Signaling Pathway
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Nrf2/NFE2L2 (L593) polyclonal antibody detects endogenous levels of Nrf2/NFE2L2 protein.
Applications Notes
Western blot (WB) analysis of Nrf2 (L593) pAb at 1:500 dilution Lane1:PC12 whole cell lysate (40ug) Lane2:Myla2059 whole cell lysate (40ug) Lane3:SGC7901 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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