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KCNB1 (phospho-S805) polyclonal antibody

Product Specifications

Background

KCNB1, also named as DRK1, KV2.1, and h-DRK1, belongs to the potassium channel family and B (Shab) subfamily. KCNB1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. The antibody is specific to KCNB1.

Structure Composition

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.

Product Name Alternative

Potassium voltage-gated channel subfamily B member 1; Delayed rectifier potassium channel 1; DRK1; h-DRK1; Voltage-gated potassium channel subunit Kv2.1; KCNB1

Swiss Prot

Q14721

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic phosphopeptide derived from human KCNB1 around the phosphorylation site of Serine805.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylation

Molecular Weight

~ 100 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

KCNB1 (phospho-S805) polyclonal antibody detects endogenous levels of KCNB1 protein only when phosphorylated at Ser805 .

Applications Notes

Western blot (WB) analysis of KCNB1 (phospho-S805) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:C6 whole cell lysate (40ug) Lane3:Panc1 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:U-87MG whole cell lysate (40ug)

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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