MXD4 polyclonal antibody

Product Specifications

Background

Max dimerization protein 4, transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Max dimerization protein 4; Max dimerizer 4; Class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4; MXD4; BHLHC12; MAD4

Swiss Prot

Q14582

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide, corresponding to Human MXD4.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 23 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MXD4 polyclonal antibody detects endogenous levels of MXD4 protein.

Applications Notes

Western blot (WB) analysis of MXD4 polyclonal antibody at 1:500 dilution Lane1:3T3-L1 whole cell lysate (40ug) Lane2:PMVEC whole cell lysate (40ug) Lane3:Hela whole cell lysate (40ug) Lane4:A375 whole cell lysate (40ug)