RHO polyclonal antibody
Product Specifications
Background
Rhodopsin is the photoreceptor in the retinal rods. It is activated by photons, transduces visual information through its cognate G protein, transducin, and is inactivated by arrestin binding. Using atomic-force microscopy, rhodopsin was found to be arranged into paracrystalline arrays of dimers in mouse disc membranes. Rhodopsin is considered to be the prototype of G protein-coupled receptors (GPCRs), and is the first GPCR for which a crystal structure was solved. Research studies have linked mutations in the gene encoding rhodopsin to retinitis pigmentosa, a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Rhodopsin; Opsin-2; RHO; OPN2
Swiss Prot
P08100
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human RHO.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 37, 75, 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RHO polyclonal antibody detects endogenous levels of RHO protein.
Applications Notes
Western blot (WB) analysis of RHO polyclonal antibody at 1:500 dilution Lane1:The Eye tissue lysate of Mouse (40ug)
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
